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[DOI] [PMC free article] [PubMed] [Google Scholar] 138.Tarkowski A, et al

Kumar et al., 2017)

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These results suggested that by preventing Sab phosphorylation, fomepizole interrupted the amplified oxidative stress cycle, stopped ROS production and halted activation of ASK1/2 ( Figure 23 )
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According to IKDSG guidelines, KD use is strictly contraindicated in patients with a deficiency of carnitine (primary), carnitine palmitoyltransferase (CPT) 1 or 2, carnitine translocase, pyruvate carboxylase, medium-chain acyl-coenzyme A (CoA) dehydrogenase (MCAD), long-chain acyl-CoA dehydrogenase (LCAD), short-chain acyl-CoA dehydrogenase (SCAD), and disorders of fatty acid -oxidation and porphyria
