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Inhibition of the mitochondrial glutamate carrier SLC25A22 in astrocytes leads to intracellular glutamate accumulation

During aggressive weight loss with Retatrutide, all three of these functions become more important than they would be in someone maintaining their weight

doi: 10.1210/en.2008-1733 117 RoaJAguilarEDieguezCPinillaLTena-SempereM

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The definition of standard reference GSH values within the different brain areas reported could lead to a better interpretation of the altered GSH levels recorded in subjects with neurological disorders, with insight into the possible role of GSH as a biomarker and therapeutic target