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When to Consider Supplementation Supplements tend to play a supportive role once foundational lifestyle factors are in place: After optimizing diet and sleep When lab work shows insufficiencies During specific life stages or increased stress, with healthcare guidance Used this way, supplements can help fill gaps rather than function as stand-alone fixes

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ScienceDirect, doi:10.1016/j.freeradbiomed.2017.12.007

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As a nutrient sensor, mTOR has important homeostatic functions to regulate energy metabolism and support neuronal growth and plasticity

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