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Increased expression of USP25 in AKI affects PKM2 (M2 isoform of pyruvate kinase, muscle), a crucial enzyme for glycolysis, which in turn causes kidney damage in AKI[105]

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Application of metabolomics techniques in COPD research Metabolomics is the study of metabolites and their branching pathways of production

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Research has shown that metformin affects various pathways involved in cancer development and progression, including AMP-activated protein kinase, mammalian target of rapamycin, and insulin-like growth factor signalling

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