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[PubMed] [Google Scholar] 59.Zemba Cilic A., Zemba M., Cilic M., Strbe S., Ilic S., Vukojevic J., Zoricic Z., Filipcic I., Kokot A., Smoday I.M., et al

Recent work has increasingly emphasized the role of these integrative systemsincluding energy availability, microbiota-derived metabolites, and neuroendocrine stress responsesin modulating or even overriding hormonal effects [15,16,17,18,19], highlighting the need for a systems-level perspective

USDA National Nutrient Database for Standard Reference Release 28

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The system would come as a kit of small-enough parts that most of it would be able to be installed by two people without heavy equipmentfor about $10,000

Additional sources: Drugs.com history (development timeline, phase 3 updates)