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GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE GLP-1 is a peptide hormone secreted by intestinal enteroendocrine L-cells, specific neurons of the solitary tract in the brainstem and some -cells in the pancreas [28]

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In another six-month, randomized, double-blind, placebo-controlled study of subjects with mild-to-moderate AD, curcumin failed to improve cognitive test scores and to reduce blood and cerebrospinal fluid (CSF) concentrations of -amyloid peptide, CSF concentrations of total and phosphorylated Tau protein, and CSF concentrations of F 2 -isoprostanes (98)

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The study found that in a mouse model of heart failure induced by the aortic band, lipid hydroperoxide and unstable iron pools were increased in cardiomyocytes