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A Busy Professional or Athlete: High stress and physical activity can deplete your nutrient stores faster

This enzymatic barrier represents a key physiological limitation, not a formulation flaw

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In support with this, several studies highlighted that cells experiencing hypoxia or mitochondrial dysfunction have decreased glutamine oxidation and rely on carbon sources, other than glucose and glutamine, to supply metabolic intermediates under hypoxic conditions 46,47,48

However, no significant adverse reactions have been reported in clinical studies