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While first-generation STING agonists showed only modest activities, new potent STING agonists in combination with other cancer therapies and improved delivery methods might improve treatment options for cancer patients

Frequently studied in sleep-related signaling investigations

Pain Patients can have pain, with or without an erection
CFTR proteins are ion channels located on the apical surface of mucous membrane and submucous gland epithelial cells [115]

Braff MH, Bardan A, Nizet V, et al

Not established for musculoskeletal applications though marketed for joint health by some vendors
