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The "L" in L-glutathione refers to the specific chemical orientation, or stereochemistry, of these amino acids

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As you mentioned, GSH can be made in the body from the amino acids l-cysteine, l-glutamic acid and glycine

2022;135:jcs259617

Such behavioral deficits in A53T mice were accompanied by the presence of elevated -synuclein monomers and aggregates (Supplemental Figure 1J) and a remarkable loss of dopaminergic neurons in the substantia nigra, as indicated by tyrosine hydroxylase (TH) staining (Figure 1C)

329 The role of ADI-PEG-20 in HGG warrants further investigation