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Lancet 395:10541062

Nausea, bloating, or appetite changes may occur, especially during early treatment phases

In HCC cell lines, upon sorafenib administration, p62 inhibited Nrf2 degradation and enhanced its nuclear accumulation

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Although the subjects had different lengths of time since the onset of the symptoms and different House-Brackmann grade points, they all responded almost to the same point after treatment, respectively over a one-month period of time

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