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RPE1 (ATCC, CRL-4000), HEK293T (ATCC, CRL-3216) and Lenti-X 293T (Takara Bio, 632180) cells were cultured in 10% FBS in DMEM

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First-in-human study of AMG 193, an MTA-cooperative PRMT5 inhibitor, in patients with MTAP-deleted solid tumors: results from phase I dose exploration

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