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Vitamin B12, or cobalamin, is a water-soluble vitamin crucial for maintaining optimal health

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Furthermore, in-vitro studies are being carried out in various laboratories, mostly using streptozotocin-induced diabetic rat/mouse models and four antidiabetic drugs explored include metformin (biguanides), sitagliptin (DPP-IV inhibitors), liraglutide (incretin mimetics) and gliclazide (sulfonyl urea receptors)

Br J Pharmacol 2014;171:115666

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Initial conditions: The initial concentration of M2 macrophages is assumed to be very low, simulating the early stages of inflammation before the accumulation of fibrotic tissue 23,42