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Nanoparticle systems enable the co-delivery of ferroptosis inducerssuch as GPX4 inhibitorsand immune checkpoint blockade agents like anti-PD-L1 antibodies directly to the tumor site, thereby increasing local drug concentration while minimizing systemic toxicity (144, 145)

doi: 10.1016/S1474-4422(11)70015-1

The genome-wide distribution of histone acetylation shows a positive correlation between enrichment at transcriptional start sites (TSS) and gene expression

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2016 May 132 (9):1308-15

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