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However, enthusiasm should always be balanced with caution

These advanced-stage therapies, targeting mechanisms such as amyloid and tau pathology, neuroinflammation, and synaptic protection, demonstrated promising efficacy and safety outcomes

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Particularly noteworthy is that FOXO4 influences not only lifespan but also the quality of aging through its interaction with the protein p53commonly referred to as the "guardian of the genome." This interaction regulates whether cells remain in a senescent, metabolically inactive state or undergo programmed cell death (apoptosis)

By integrating careful classification, understanding of the healing process, and comprehensive clinical evaluation, clinicians can implement interventions that support tissue regeneration, minimize complications, and enhance patient outcomes

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