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Single-cell suspensions of lymphocyte were harvested from mouse liver

Antigen-specific tolerance This strategy aims to retrain the immune system to recognize islet antigens as self. Approaches include vaccines (e.g., with GAD65) or nanoparticles designed to deliver self-antigens in a tolerogenic context to antigen-presenting cells, potentially inducing antigen-specific Tregs or anergy in autoreactive T cells [122]

Eli Lilly & Company and the National Center for Advancing Translational Sciences (2014)

Saccheri, F

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While PDE5 is almost undetectable in heathy cardiomyocytes, localized at Z-disks, enzyme expression is significantly upregulated and diffusely distributed in pathologic conditions, such as congestive heart failure, right ventricular hypertrophy, overload hypertrophy, ischemic cardiomyopathy (5558)