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head CT scan Potential indications may include: Possible head trauma with risk for intracranial hemorrhage Clinical concern regarding cerebral edema general supportive measures general supportive measures Intubation may be needed for airway control

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Roles of Wnt8a during formation and patterning of the mouse inner ear

Sumi et al., 2023)

It is notable that the GSH-induced airway changes in the third challenge were of lesser magnitude than in the other two, possibly because airway tone was conditioned by the previous nebulization with placebo, although changes in the degree of bronchial hyperresponsiveness by itself through the whole study also could play a role

Animals were monitored daily over the duration of the study for general health, food and water consumption