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For example, SUFU is not conserved and the homolog of the transcription factor Gli, TRA-1, is involved in sex determination and gonad development in males and hermaphrodites 24

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- support of wound healing activities*

Furthermore, overexpression of D2hgdh from a UAS-D2hgdh transgene reduces D-2HG accumulation in flies expressing UAS-Idh-R195H , indicating that Drosophila D2hgdh also functions to degrade D-2HG (REITMAN et al

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