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Description
Neuroinflammation results in the inhibition of the neuronal 2-oxoglutarate dehydrogenase complex (OGDHC)a tricarboxylic acid (TCA) cycle enzyme which inhibits the uptake of glutamate by mitochondria (Vaglio-Garro et al

Glutamate-treated PC12 cells and chronic unpredictable mild stress (CUMS)-induced rats were established as models of depression in vitro and in vivo respectively

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HaloTag: The HaloTag is based on a modified haloalkane dehalogenase and allows for both in vitro and in vivo protein labeling and purification
