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Description
This rapid, intraoperative destruction of the transplanted organ despite well-controlled blood pressure on an ACE inhibitor is characteristic of hyperacute rejection, a process mediated by preformed antibodies in the recipient

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A.Riehle-ColarussoT.et al (2020)

Clinicians should be candid with patients about the gap between mechanistic plausibility and proven, durable clinical benefit, and should avoid presenting sermorelin as an established anti-aging treatment

Just remember that each additional needle puncture increases contamination risk
