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However, excessive maternal caffeine exposure (100 mg/kg/day, intraperitoneally) during pregnancy has been indicated in inducing cataracts (130), suggesting that caution when consuming a high quantity caffeine is necessary for pregnant women

At present, insufficient data exists to support surveillance for these cancers outside a clinical trial

Lactate can also diffuse through astrocyte gap junctions (Rouach et al., 2008), which remain open during ischemia (Cotrina et al., 1998), facilitating the beneficial flux of lactate within the astrocytic network
