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The Result: 3.7V + 3.7V = 7.4V

Ceramide is synthesized de novo in the cytoplasmic leaflet of the ER and metabolized to glucosylceramide (GlcCer), a precursor of more-complicated glycosphingolipids 3

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Diarrhea is another commonly reported gastrointestinal side effect that may range from mild loose stools to more significant episodes that could lead to fluid and electrolyte imbalances if severe or prolonged

Participants received 20, 40 or 60 mg/kg/d or placebo and it was reported that the 60 mg/kg/d treatment was discontinued due to it exacerbating the ataxia symptoms in 2 patients (Pandolfo et al., 2014)

A CDC homolog in Arabidopsis is essential for meiosis, as shown by RNA interference-induced gene silening