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Of the 49 metabolic pathways analyzed, 15 showed significant differences after treatment, with the mTOR signaling pathway, alanine metabolism, and arginine biosynthesis pathway being particularly relevant

Another limitation of the study is determining if the appropriate dose of NAC was given

Recently, therapeutic strategies involving the administration of growth factors have been advocated to enhance tendon regenerative healing

GI dysfunction, a common comorbidity in PD, further contributes to fluctuations in levodopa absorption and plasma concentrations, thereby triggering or exacerbating the on-off phenomenon [86, 87]

Many studies have shown the protective effects of NAC for neonatal animals immune challenged with bacterial lipopolysaccharide (LPS) endotoxin, particularly studies involving piglets [13,14]

Of importance, additional work is required to elucidate the mechanisms of lipid peroxides triggering necroptosis and upstream kinases involved in this process