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From a GABAergic perspective, adaptive plasticity mechanisms may be impaired in the aged brain due to a prevalenceof GABA A receptors showing different pharmacological kinetics and response to GABA compared to young animals

doi: 10.3389/fimmu.2025.1477437 Received 07 August 2024 Accepted 20 January 2025 Published 10 February 2025 Volume 16 - 2025 Edited by Nejat Dalay, Istanbul University, Trkiye Reviewed by Junwei Luo, Henan Polytechnic University, China Mario Perez-Medina, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico Updates Copyright 2025 Hu, Tian, Liu, Hou, wu, Wang and Shu

This treatment involves delivering vitamins, minerals, and hydration directly into the bloodstream for maximum absorption

Conclusions Our results indicate that in aged female mice, 12 weeks of B12 supplementation improved skeletal muscle mitochondrial biology, specifically improving mitochondrial DNA content, morphology, and proteins

For researchers managing a multi-month protocol, this planning functionality prevents supply gaps

doi: 10.1016/j.compbiomed.2022.105224 [DOI] [PubMed] [Google Scholar] 98.Tanabe K, Yamamoto A, Suzuki N, et al