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However, the growth of non-pathogenic organisms does typically render the product undesirable to a consumer and is considered to have ended the shelf life of the product

Washington, DC, USA: 2006

Ramachandra R, et al

The outcome suggested that a transient and limited increase in gut permeability compared with the unregulated breach of the gut barrier function due to the TJ deregulation and epithelial cell apoptosis can rather lead to a dominant regulatory immune response to gut microbiota antigens and to a net anti-inflammatory effect