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5.4 Allergy and Hypersensitivity There have been post-marketing reports of hypersensitivity and anaphylaxis associated with the use of acetaminophen

Marincola Smith, P, Tomita, K, Cass, SH, Hirata, Y, Pan, C, Shen, SE, Wang, X, Wang, XS, Williams, LA, Arvide, M, To, C, Rajaram, R, Rice, DC, Hofstetter, WL, Antonoff, MB, Mehran, RJ, Vaporciyan, AA, Walsh, GL, Maxwell, JE, Snyder, RA, Kim, M, Tzeng, CD, Badgwell, BD, Mansfield, PF, Katz, MH, Swisher, SG , Lee, JE, Ikoma, N

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The mechanisms of MSMs antioxidant activity includes increasing the activity of superoxide dismutase [6,8,20,3032], enhancing total antioxidant capacity (TAC) [68,10,33,34], reducing malondialdehyde (MDA) [8,10,12,13,20,31,32,35], and regulating the glutathione system (e.g., glutathione synthesis and glutathione peroxidase activity) [7,8,13,20,32,35]