dsip certificate of analysis PEPTIDE 2MG/5MG VIAL – UMBRELLA Labs CJC-1295 No DAC (5mg) 5-pack

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Follow-up Repeat metabolic markers after 8-12 weeks or sooner if appetite, hydration, vomiting, or glucose symptoms change

Published in NEJM 2023

staggered titration Cycle driver GI tolerance sets the pace Tirzepatide Loading 2.5 5 7.5 10 12.5 mg (every 4 weeks) Frequency Once weekly Maintenance 15 mg weekly Route SubQ Cagrilintide Loading Start Week 9: 0.25 0.5 1.0 1.7 mg Frequency Once weekly Maintenance 2.4 mg weekly Route SubQ Weekly Schedule Example (Maintenance Phase) Monday Tirzepatide 15 mg (one site) + Cagrilintide 2.4 mg (different site) Tuesday No injections Wednesday No injections Thursday No injections Friday No injections Saturday No injections Sunday No injections Both compounds are once weekly

Administration Differences TB-500 distributes systemically regardless of injection location due to its low molecular weight and long half-life

Ensure proper injection technique