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For example, a previous study on PD brains showed an increase in lipid peroxidation products, such as 4-hydroxinonenal, and in protein crosslinking and fragmentation [51], suggesting that oxidative stress may affect other brain regions apart from the SN

Research suggests that glutathione has three modes of action on hyperpigmentation: Inhibition of tyrosinase activity Tyrosinase inhibition is the major mechanism by which glutathione lowers dark spots, patches, and uneven skin tone

Dettelbach and Bennett, 1979)

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Glutathione helps to regulate several cellular events, such as gene expression, protein and DNA synthesis, immune response and cell growth