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Di L, Kems EH, Gao N, Li SQ, Huang Y, Bourassa JL, and Huryn DM (2004) Experimental design on single-time-point high-throughput microsomal stability assay

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Phase-I metabolites are highly apt to form adducts with proteins and nucleic acids because of their electrophilic character
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doi: 10.1021/np0005457
