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As expected, the incidence of thrombocytopenia in patients with hematologic cancers is higher, and it is worth noting that many of these patients suffered from thrombocytopenia before beginning chemotherapy (Table 1) [9]

The equivalent arginine-serine network in Rattus norvegicus OAT1 has been implicated in gating dynamics and the allosteric modulation of OAT1 by chloride 25 , with chloride binding to R466 rOAT1 in the inward-facing conformation stabilising this network

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doi:10.3389/fneur.2014.00206

doi: 10.1007/s11916-025-01418-8 Parvat Kuwar Chhetri, Frederick M

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