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Niacinamide (12 mg): This form of Vitamin B3 is essential for cellular energy metabolism and antioxidant functions

The MS-based proteomics data have been deposited to the ProteomeXchange Consortium ( via the PRIDE partner repository with the dataset identifier PXD063561

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SUGGESTED DAILY USE: Take two (2) capsules daily, with or without food, or as directed by your healthcare professional

RNA Sequencing of proband from Family 2 (II.2) RNA was isolated from tumour tissue of the proband using a Qiagen Kit as per manufacturers instructions

Non-linear dimensional reduction techniques were applied to visual data in UMAP plot format