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In a multiplexed assay, each spectrally unique bead is labeled with antibodies specific for a single target protein, and bound proteins are identified with biotinylated antibodies and streptavidinR-phycoerythrin (RPE)

Thereafter, immunotherapeutic efficacy and drug sensitivity were predicted using the TIDE platform and the oncoPredict package

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Corrector/potentiator dual therapy resulted in small improvements in quality of life (QoL) and respiratory function and a reduced frequency of pulmonary exacerbations