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Multiple independent groups have replicated the finding

The assay is based on the conversion of citrate to isocitrate, to -ketoglutarate, which results in the production of NADPH

Engal E, Zhang Z, Geminder O, Jaffe-Herman S, Kay G, Ben-Hur A, et al

What is Glutamate

Journal of Receptors and Signal Transduction, 2012 , 113

Rather than treating these domains independently, we propose a unifying framework in which melatonin functions as a physiological hub coordinating temporal organization and cellular protection
