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OAS1 induces endothelial dysfunction and promotes monocyte adhesion through the NFB pathway in atherosclerosis

doi: 10.1038/ncomms8758

This involves hydrolysis or transpeptidation of GSH at the plasmembrane by -glutamyl transpeptidase (GGT), and intracellular metabolism of -glutamyl amino acid derivatives by glutamyl cyclotransferases (GGC) and 5-oxoprolinase (5-OPase) to produce free glutamate

Fitzpatrick, A.M., D.P

There are several possible mechanisms whereby higher vitamin D levels could have a protective effect against damage caused by smoking on lung function
