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Concluding remarks Many of the foundational studies of the ascorbateglutathione pathway in the 1970s and 1980s were conducted in plant species such as spinach and pea

C.TumasV.LiuM.ZhengW.HaackeE

B.TrivediA.PfankuchT.RaberJ.WendlandM.et al (2009)

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Gliotoxin was administrated to female C57BL/6 mice immunized with myelin oligodendrocyte glycoprotein with a dose of 1 mg/kg, which can aggravate the symptom of neuroinflammation via the upregulation of inflammatory genes, including T-box transcription factor (TBX21), inducible nitric oxide synthase (iNOS), arginase 1 (ARG1), and cytokines such as IFN-, IL-17, and IL-2 [48]

doi: 10.1016/j.cbi.2018.12.006