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While these agents often spare normal proliferating tissues, they introduce new toxicity patternssuch as dermatologic reactions, QT prolongation, diarrhea, and hepatotoxicityoften linked to the pathways they target in normal tissues

However, strengths of the study include the community-based recruitment, the unmedicated and mostly medication-nave MDD group, and the relatively large control sample that matched MDD cases in terms of education and other sociodemographic variables [7]

however, the B-vitamin treatment group experienced a smaller loss of gray matter compared to the placebo group (0.5% vs

There are two safety considerations that warrant specific attention: The angiogenesis and tumor promotion concern

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