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Prolonged GH elevation can reduce insulin sensitivity and affect blood glucose management

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Another 5 -reductase-2 gene polymorphism, A49T , which changes an alanine to a threonine residue at amino acid 49 with an increase in 5 -reductase activity has found to be associated with prostate cancer risk in African-American, Latino and Hispanic men, and be most common in African-American and Latino men with advanced prostate cancer 81

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