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Description
Triggered by mitochondrial oxidative stress, Ca 2+ overload, dysregulation of iron homeostasis, mitochondrial DNA defects, and disruption of mitochondrial quality control (MQC), programmed cell death subsequently ensues encompassing apoptosis, pyroptosis, necroptosis, and ferroptosis [17]
& Mark, V
The combined action of erastin and the apoptotic agent TRAIL was shown to mediate apoptosis via activation of caspases (154), suggesting a possible mechanism of interaction between ferroptosis and apoptosis
G.PuigjanerJ.CascanteM.LeeW
2023;42 doi: 10.1016/j.celrep.2023.112666
doi: 10.1038/mp.2015.166
