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While this finding further highlights age-specific effects of GA exposure, it is unclear if these differences are simply explained by discrepant mitochondrial stress levels, or if they represent true deviations in the cellular response

23 Due to the superior efficacy of antioxidative enzymes in scavenging ROS compared to exogenous molecules, the antioxidative effects mediated by NRF2 are notably significant

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It is an important factor in determining the architectural structure of a lesion and its clinical behavior

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upregulated during inflammation and stress Both isoforms convert arachidonic acid to PGH, the common precursor for multiple eicosanoid mediators