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The NIH highlights that many claims about anti-aging or skin lightening show some positive results with no adverse effects throughout the study

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Gel formulations of vitamin B12 are somewhat new and applied into the nostrils (intranasally)

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While the metabolic evidence is limited to studies on rats,(1) what we do know is that B12 plays a major role in red blood cell production and formation, anemia prevention and healthy nervous system function