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[3] The clostridium perfringens enterotoxin (CPE) mediating the disease is heat-labile (inactivated at 74 C (165.2 F))

Green Frogs overwintering in ice-free waters may be active on warm winter days

[DOI] [PubMed] [Google Scholar] 183.Toyoda H, Atsukawa M, Watanabe T, Nakamuta M, Uojima H, Nozaki A, Takaguchi K, et al

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For the differential diagnosis between Spitz's nevus and spitzoid melanoma, the following light microscopic features favor melanoma: large size, asymmetry, complex growth pattern, presence of mitotic figures in deep dermal melanocytes, atypical mitotic figures, thinned epidermis with effaced rete ridges (consumption of the epidermis), lack of maturation, and absence of Kamino bodies