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[DOI] [PMC free article] [PubMed] [Google Scholar] (360).Ting CP

The enzyme apparently manipulates the pKa to facilitate the deprotonation of bicarbonate

Nevertheless, HO lipid accumulation is reduced and hepatocyte apoptosis is inhibited when HOs and adipose-derived MSCs are co-cultured (265)

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-/- homozygotes also present with some loss of function in cerebral vessels and abnormal lipid deposition in the aorta and disruption of the laminar structure of the cerebellum with no obvious changes in the cortex or cerebrum ( Unlike MTHFR and CBS knockout mice, dietary induction of HHcy allows for age related HHcy to be studied

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