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doi: 10.1097/00001503-200208000-00004

Len-Lpez, A., Morales-Pealoza, A., Martnez-Jurez, V

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While the familial forms of PD, that have been described, involve mutations in a number of genes (Trinh and Farrer, 2013), mitochondrial dysfunction, neuroinflammation and environmental factors are increasingly appreciated as key determinants of dopaminergic neuronal susceptibility in PD, and are a feature of both familial and sporadic forms of the disease (Ryan et al., 2015)