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Other reasons that may cause low vitamin B12 deficiency in the body include alcohol consumption, having Sjgren's syndrome over six times, age-related factors such as chronic atrophic gastritis, and rare genetic disorders such as Imerslund-Grsbeck syndrome, and autoimmune conditions such as lupus or type 1 diabetes are associated with an increased risk of low B12
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Li G, Fang S, Shao X, Li Y, Tong Q, Kong B, Chen L, Wang Y, Yang J, Yu H (2021a) Curcumin reverses NNMT-induced 5-fluorouracil resistance via increasing ROS and cell cycle arrest in colorectal cancer cells

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Nature Lee E, Walker C, Ayadi B

It converts a substance called methylmalonyl-CoA into succinyl-CoA