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In one case report, post-mortem examination 10 years post-transplant showed intense gliosis of bilateral caudate nuclei and putamen, as well as the unfortunate overgrown of masses and a cyst from the transplant

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It is important to note that curcumin exhibits a biphasic dose-response relationship: lower doses activate protective pathwaysincluding increased total glutathione (GSx) and GST activitywhile higher doses deplete GSH, reduce related metabolites (e.g., taurine, homocysteine), and may induce pro-oxidant effects or cellular toxicity (Scharstuhl et al., 2009)

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The lack of adequate vitamin B12 from sources such as meat, eggs, and dairy, can lead to deficiencies causing anemia, intestinal issues, and other medical conditions
