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Description
Similarly, impeding the CYFIP1/Rac1 interaction or the CYFIP1/NCKAP1 dimer formation, could have a dual beneficial effect in concomitantly restoring normal levels of protein synthesis and actin dynamics, both processes being dysregulated in FXS

The binding of the RGD motifs to the V integrins expressed in tumor endothelial cells induces the protease-mediated cleavage of the iRGD peptide, producing two peptides, namely, CRGDR/K and GPDC

However, excessive production or metabolic imbalance of these highly reactive and unstable free radicals can lead to oxidative stress (OS)

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and Cell

High concentrations of tHA inhibited the expression of autophagy-related proteins beclin1 and LC3II in human PDLSCs (hPDLSCs), inducing excessive ROS production and leading to cell damage and apoptosis
