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Statistical significance was determined using one-way ANOVA followed by Tukey's post hoc test or Kruskal-Wallis followed by Dunn's post hoc test

Beyond Hollywood, glutathione is massively popular in Asia, particularly in East and Southeast Asian countries where lighter skin is often culturally associated with beauty and youth

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Upon its efflux from cells, oxidised glutathione is exposed to the sequential action of enzymes located on the external face of the cell membrane: -glutamyl transpeptidase (GGT) generates glutamate 94 and the cysteinylglycine dipeptide, which is degraded by dipeptidases such as aminopeptidase N (APN), thereby releasing cysteine and glycine