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Song et al showed that decreasing periplasmic GSH by deleting the GSH exporter CydD triggers the CpxR/SoxS two-component systems, upregulating the AcrAB-TolC pump and lowering intracellular drug accumulation

This approach sounded promising, but transplantation of bone marrow stem cell lines did not always lead to the desired results and was ineffective, resulting in potential harm to the patient

In this narrative review, we summarized the current evidence on the mechanism of action, clinical pharmacology, and applications of amylin in the field of diabesity

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In April 2026, the FDA removed BPC-157 from its Category 2 list (substances with safety concerns that were previously restricted from compounding)

Journal of Medicinal Chemistry, 57 (22), 9220