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For example, a study involving high-intensity interval swimming, supplemented with 2 g of LC twice daily for a week, found no significant changes in blood lactate or pH levels, suggesting limited metabolic effects (Qin et al
gain-of-function mutations in voltage-gated sodium channel genes increase neuronal excitability and are associated with PDPN
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However, this conclusion is not completely justified because changes in liver volumes were not measured
