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Inflammaging: a new immune-metabolic viewpoint for age-related diseases

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Array hybridization was performed using an Affymetrix GeneChip Human Gene 2.0 ST Array

The formation of the autophagosomal membrane is regulated by class III PtdIns3K complexes containing Vacuolar protein sorting-associated protein 34 (Vps34), Vps15, Beclin1, and Atg14, which regulates the process that generates PtdIns(3)P-rich membranes [16]