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This conservation is not surprising as oxidative stress is an inevitable byproduct of aerobic respiration, and GSH is an important antioxidant that mitigates the effects of reactive oxygen species (ROS), such as hydrogen peroxide

The above-mentioned mechanism of the skin-whitening efcacy of topical GSSG and its relationship to GSH are not clear and are no more than speculation

Dysregulation may result in localized inflammation, impairing nutrition absorption and potentially triggering systemic metabolic disorders

Phytochemistry 103:114122 Wei S, Sun T, Du J, Zhang B, Xiang D, Li W (2018) Xanthohumol, a prenylated flavonoid from Hops, exerts anticancer effects against gastric cancer in vitro

Binding to the IGF1R initiates intracellular signaling

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